Zetia (ezetimibe) lowers the amount of cholesterol soaked up by the body.
Zetia is made use of to deal with high cholesterol.
Zetia is sometimes supplied other cholesterol-lowering medications.
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Important information
Zetia is only part of a full program of therapy that additionally includes diet plan, exercise, and also weight control. Follow your diet regimen, medication, and also exercise routines very carefully.
Some cholesterol medications should not be taken at the exact same time. If you take Zetia with another cholesterol medication, follow your physician’s dosing directions extremely meticulously.
You need to not make use of Zetia if you have modest to severe liver disease. You should not utilize ezetimibe with a “statin” cholesterol medicine if you have energetic liver disease, or if you are pregnant or breast-feeding an infant.
Call your physician today if you have inexplicable muscle mass pain, inflammation, or weak point specifically if you also have heat, unusual exhaustion, as well as dark tinted pee.
Before taking this medicine
You should not utilize Zetia if you are sensitive to ezetimibe, or if you have:
moderate to extreme liver condition.
You must not make use of ezetimibe with a “statin” cholesterol medication (Zocor, Lipitor, Crestor, and others) if:
you have energetic liver condition;
you are expecting; or
you are breast-feeding a baby.
To make certain Zetia is secure for you, tell your physician if you have:
kidney illness; or
a thyroid condition.
Prior to you start taking Zetia, inform your medical professional if you already take a statin cholesterol medication.
Some cholesterol drugs can create a problem that causes the failure of skeletal muscle mass cells, causing kidney failing. This problem might be most likely to happen in older adults as well as in individuals who have kidney illness or inadequately managed hypothyroidism (underactive thyroid).
You need to not take ezetimibe with a statin medicine if you are expecting or breast-feeding.
It is not understood whether Zetia alone will damage an expected child. Tell your physician if you are expectant or strategy to end up being expectant. Usage effective birth control to stop pregnancy while you are using ezetimibe with a statin medicine.
It is not understood whether ezetimibe alone enters breast milk or if it might damage a nursing child. Tell your doctor if you are breast-feeding a baby. You need to not breast-feed if you take Zetia with a statin medicine.
Side Effects
uncommon muscular tissue weakness, tenderness, or discomfort; nausea or vomiting, stomach discomfort, low high temperature, anorexia nervosa, dark urine, clay-colored feces, jaundice (yellowing of the skin or eyes); breast pain; pancreatitis (serious discomfort in your top belly infecting your back, nausea and vomiting, fast heart price); or.
Get emergency scientific aid if you have indicators of an allergic response to Zetia: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some cholesterol drugs could trigger a condition that leads to the failure of skeletal muscle mass cells, resulting in kidney failure. Call your doctor right now if you have unusual muscle mass discomfort, swelling, or weakness especially if you additionally have high temperature level, uncommon exhaustion, as well as dark colored pee.
Adverse effects could be more probable in older grownups.
Typical Zetia negative effects could include:
muscle mass or joint discomfort;
stale nose, sinus discomfort, aching throat;
looseness of the bowels; or
discomfort in an arm or leg.
This is not a complete checklist of adverse effects and others could take place. Call your physician for clinical suggestions about negative effects. You could report negative effects to FDA at 1-800-FDA-1088.
Dosing Information
Common Adult Dose for Hyperlipidemia:
10 mg daily with or without food.
Common Adult Dose for Sitosterolemia:
10 mg daily with or without food.
Dosage
Zetia is readily available in 10-milligram tablet computers, as well as the common dosage is one tablet computer daily. The drug can be taken with or without a meal.
F.A.Q
What other drugs will affect Zetia?
Tell your medical professional concerning all your present medications and also any kind of you start or quit making use of, particularly:
cyclosporine; or
a blood thinner (warfarin, Coumadin, Jantoven).
This listing is not full. Various other medicines may engage with Zetia, consisting of prescription as well as over the counter medicines, vitamins, as well as natural products. Not all feasible interactions are provided in this medicine guide.
What Happens If I Missed Dose?
If you miss out on a dose, take it when you keep in mind. Miss the dosage if it is practically time for your following dosage. Do not take extra medication to earn for a missed dose. Do not take greater than one dose of Zetia a day.
Mechanism Of Action
Mechanism Of Action. Ezetimibe decreases blood cholesterol by preventing the absorption of cholesterol by the tiny intestine. In a 2-week medical study in 18 hypercholesterolemic patients, ZETIA hindered digestive tract cholesterol absorption by 54%, compared with sugar pill.
Does zetia cause weight gain?
Inning accordance with the recommending details, Zetia does not assist individuals slim down. However, while taking Zetia, a person should remain to comply with a cholesterol-lowering diet as directed by their doctor. Some of the negative effects that could accompany Zetia include looseness of the bowels, exhaustion, and joint pain.
What is the generic version of Zetia?
Ezetimibe has a gadget of activity that differs from those of various other training courses of cholesterol-reducing compounds (statins, bile acid sequestrants [products], fibric acid by-products, as well as also plant stanols). Ezetimibe does not prevent cholesterol synthesis in the liver, or increase bile acid discharging.
Zetia vs Lipitor
Zetia (ezetimibe) can improve your cholesterol as well as can be made usage of as an option to statins. Lipitor (atorvastatin) enhances your cholesterol degrees and also is a typical first therapy for individuals with high cholesterol or heart problem. Can be used with various other medicines to increase cholesterol.
How should I take it?
Take Zetia precisely as it was prescribed for you. Adhere to all directions on your prescription label. Do not take this medicine in bigger or smaller quantities or for longer compared to advised.
Zetia is typically taken daily. Take the medication at the same time each day.
You might take this medication with or without food.
Zetia might be taken at the exact same time with fenofibrate, or with a statin medicine such as atorvastatin, lovastatin, simvastatin, pravastatin, or fluvastatin.
Some cholesterol drugs need to not be taken at the very same time.
If you additionally take cholestyramine, colestipol, or colesevelam: Wait at the very least 4 hrs after taking any one of these medicines prior to you take ezetimibe. You could in addition take ezetimibe 2 humans resources prior to taking any of these other medications.
You should not take ezetimibe with gemfibrozil.
You might need regular blood examinations to check your liver function if you take ezetimibe with a statin medication.
It might occupy to 2 weeks before your cholesterol degrees improve. Maintain utilizing your medication as routed. You will certainly need frequent blood examinations to determine your cholesterol levels.
Zetia is only component of a complete program of therapy that additionally includes diet, exercise, as well as weight control. Follow your diet plan, medicine, and exercise regimens really carefully.
Store at space temperature far from dampness as well as warmth.
What happens if I miss a dose?
Take the missed out on dose as quickly as you keep in mind. Avoid the missed out on dose if it is nearly time for your next scheduled dose. Do not take extra medication to earn up the missed out on dose.
What should I avoid?
Stay clear of eating foods that are high in fat or cholesterol. Zetia will certainly not be as effective in lowering your cholesterol if you do not comply with a cholesterol-lowering diet plan.
Can you lose weight on Zetia?
Zetia along with diet has actually been shown in order to help reduce overall cholesterol and LDL (bad) cholesterol. Inning accordance with the suggesting information, Zetia does not assist people slim down. Nevertheless, while taking Zetia, a person should remain to follow a cholesterol-lowering diet plan as directed by their physician.
Can Zetia cause kidney damage?
In uncommon situations, cholesterol-lowering medicine could trigger a condition that causes the breakdown of skeletal muscle cells. This problem could lead to kidney failing. Call your doctor at the same time if you have unexplained muscle mass discomfort or inflammation, muscle mass weakness, high temperature or flu symptoms, and dark tinted pee.
What is the generic medication for Zetia?
Ezetimibe is an oral medicine that is utilized for the therapy of raised blood cholesterol. The most typically made use of class of medications for lowering cholesterol levels, the statins, act by preventing the production of cholesterol by the liver.
How much does Zetia cost without insurance?
This Zetia cost overview is based on utilizing the Drugs.com discount rate card which is approved at most U.S. pharmacies. The expense for Zetia oral tablet 10 mg is around $162 for a supply of 30 tablet computers, depending upon the drug store you go to. Prices are for cash money paying clients just and also are not legitimate with insurance plans.
Is Zetia considered a statin drug?
Zetia (ezetimibe) is a medicine utilized to assist deal with high cholesterol, as well as operates in a various method than statins, which reduced cholesterol by 35 to 60 percent in many patients and lower the danger of cardiovascular disease amongst them. Statins function by blocking an enzyme used by the liver to generate cholesterol.