This medicine is made use of to treat looseness of the bowels. It assists to decrease the number and also frequency of defecation. It works by reducing the activity of the intestinal tracts.

Diphenoxylate resembles numbing pain reducers, however it acts mainly to reduce the intestine. Atropine belongs to a course of medicines called anticholinergics, which aid to run out body fluids and also slow-moving gut activity.

How to use Lomotil

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Take this drug by mouth, generally 4 times a day or as directed by your medical professional. Dose is based on your clinical problem and also feedback to therapy. In children, dosage is additionally based on weight.

If you should proceed therapy when your looseness of the bowels is regulated, your medical professional may route you to decrease your dosage. Do not increase your dosage, take it regularly, or use it for longer than recommended.

A liquid formula is available for use in children. Usage just the dropper that includes the bottle to thoroughly determine out each dose.

It is essential that you consume the proper quantity of fluids as well as minerals (electrolytes) to protect against loss of body water (dehydration). Inform your doctor right away if you develop signs of dehydration (e.g., severe thirst, lowered urination, muscle mass cramps, weak point, fainting).

You might also require to transform to a bland diet plan during this time around to minimize irritation to your stomach/intestines. Consult your medical professional or pharmacologist for additional information.

This medication might create withdrawal reactions, particularly if it has actually been used on a regular basis for a lengthy time or in high doses. In such cases, withdrawal signs (such as tummy pains, nausea or vomiting, throwing up) might occur if you unexpectedly quit utilizing this drug.

To avoid withdrawal responses, your doctor may minimize your dose gradually. Consult your physician or pharmacologist for even more information, and report any type of withdrawal reactions today.

Notify your physician if your condition does not enhance after 2 days.

Side Effects Of Lomotil

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See additionally Preventative measures for negative effects seen in kids.

Sleepiness, wooziness, headache, fatigue, blurred vision, completely dry mouth, as well as anorexia nervosa might occur. If any of these results persist or get worse, inform your medical professional or pharmacologist without delay.

Bear in mind that your medical professional has prescribed this drug since he or she has actually evaluated that the advantage to you is above the danger of side effects. Many individuals utilizing this medication do not have significant side effects.

Inform your medical professional as soon as possible if any one of these not likely yet major adverse effects happen: stomach/abdominal discomfort or swelling, serious nausea, throwing up, mental/mood changes (e.g., confusion, anxiety), restlessness, numbness/tingling of arms/legs.

Obtain medical aid as soon as possible if you have any very major negative effects, consisting of: eye pain/swelling/redness, vision adjustments (such as seeing rainbows around lights in the evening).

A really severe allergic response to this drug is rare. Nonetheless, look for instant clinical focus if you observe any type of symptoms of a significant allergy, including: breakout, itching/swelling (especially of the face/tongue/throat), serious lightheadedness, problem breathing.

This is not a total listing of possible side impacts. If you see other results not noted above, call your doctor or pharmacist.


Before taking diphenoxylate with atropine, inform your physician or pharmacist if you are delicate to either drug; or to hyoscyamine; or if you have other allergic reactions.

This item might consist of non-active active ingredients, which can trigger allergic actions or various other troubles. Speak with your pharmacologist for even more details.

This medication should not be made use of if you have specific clinical conditions. Prior to using this medication, consult your physician or pharmacist if you have: liver disease (e.g., obstructive jaundice, cirrhosis), looseness of the bowels triggered by particular kinds of infections (Clostridium difficile-associated diarrhea complying with recent antibiotic therapy, bacterial infection of the intestine brought on by E. coli, Salmonella, Shigella).

Before utilizing this medicine, tell your doctor or pharmacist your case history, particularly of: present dehydration or mineral discrepancy, a particular type of bowel illness (acute ulcerative colitis), personal or family members background of glaucoma (angle-closure type).

This drug may make you lightheaded or drowsy. Do not drive, utilize equipment, or do any activity that calls for awareness till you make certain you can do such activities safely. Restriction alcohols.

Liquid types of this product might have alcohol. Care is recommended if you have alcoholism or liver disease. Ask your physician or pharmacologist about using this product securely.

This medication is not recommended for use in children more youthful compared to 2 years. Care is advised when using this drug in kids, specifically those with Down’s disorder, since they may be a lot more delicate to the following negative effects: high fever, quick heartbeat, lowered urination, flushing, completely dry skin/mouth, thirst. Very severe (perhaps serious) results may occur if too much of this drug is taken by kids.

While pregnant, this medicine needs to be used just when clearly needed. Discuss the risks and also benefits with your physician.

This medicine enters breast milk. Consult your doctor prior to breast-feeding.


Your doctor or pharmacologist could already know any kind of possible medication communications and may be monitoring you for them. Do not start, stop, or alter the dosage of any medicine prior to consulting your medical professional or pharmacist first.

This medication must not be utilized with the complying with drugs since extremely major interactions may happen: ambenonium, pramlintide.

If you are presently using any of these drugs provided above, tell your doctor or pharmacologist prior to starting diphenoxylate with atropine.

Prior to utilizing this medication, educate your medical professional or pharmacologist of all prescription and likewise nonprescription/herbal items you could use, particularly of: MAO avoidances (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine), naltrexone, potassium tablets/capsules.

Inform your medical professional or pharmacist if you likewise take medications that trigger sleepiness such as: specific antihistamines (e.g., diphenhydramine), medication for sleep or stress and anxiety (e.g., alprazolam, diazepam, zolpidem), muscle mass relaxants, narcotic painkiller (e.g., codeine), psychological medications (e.g., chlorpromazine, risperidone, amitriptyline, trazodone).

Examine the labels on all your medicines (e.g., cough-and-cold items) since they might consist of drowsiness-causing components. Ask your pharmacologist concerning making use of those products securely.

This paper does not contain all possible interactions. Consequently, prior to utilizing this item, inform your medical professional or pharmacist of all the items you use. Keep a list of all your drugs with you, and share the checklist with your physician as well as pharmacologist.

Lomotil Dosage

Management of Looseness Of The Bowels in Patients 13 Years old and Older

Lomotil is advised as adjunctive treatment for the monitoring of looseness of the bowels in individuals 13 years old and also older. Take into consideration the dietary standing and also degree of dehydration in clients before initiating treatment with Lomotil.

The usage of Lomotil need to be gone along with by ideal liquid as well as electrolyte therapy, when indicated. If serious dehydration or electrolyte inequality is existing, do not carry out Lomotil till appropriate restorative therapy has really been recommended (see WARNINGS).

First and Maximum Recommended Dose in Patients 13 Years of Age and Older

The preliminary adult dose is 2 Lomotil tablets four times everyday (optimal total daily dose of 20 mg each day of diphenoxylate hydrochloride). Many clients will need this dosage up until first control of looseness of the bowels has been accomplished. Professional renovation of severe diarrhea is generally observed within 48 hrs.

Dosage after Initial Control of Diarrhea

After initial control has in fact been acquired, the Lomotil dosage could be lowered to please private requirements. Control might usually be preserved with as low as 2 Lomotil tablet computers daily.

Duration of Treatment

If scientific enhancement of persistent looseness of the bowels after therapy with the optimum recommended daily dosage is not observed within 10 days, discontinue Lomotil as symptoms are unlikely to be managed by more administration.

Overview of Lomotil (Diphenoxylate) for Dogs and Cats

Diphenoxylate comes from a course of medications understood as opiate agonists (morphine by-product). Diphenoxylate, likewise recognized as Logen ®, Lomotil ®, as well as Lonox ®, is mainly utilized to deal with looseness of the bowels as well as colitis in pets and pet cats. It additionally has anti-coughing residential properties.

Diphenoxylate reduces the intestinal system, decreases digestive secretions and enhances absorption of liquids.

Diphenoxylate is a prescription medication and can only be obtained from a vet or by prescription from a vet.

This drug is not accepted for use in pets by the Food and also Medicine Administration but it is suggested legitimately by veterinarians as an extra-label drug.

Trademark Name of Diphenoxylate
This medicine is signed up for use in human beings just.
Human solutions: Logen ® (Goldline), Lomotil ® (Searle), Lonox ® (Geneva) and also numerous common brands.
Vet formulas: None

Precautions and Side Effects

While generally secure and reliable when prescribed by a vet, diphenoxylate could cause adverse effects in some animals.

Diphenoxylate should not be made use of in animals with known hypersensitivity or hatred the medicine. Not advised for use in young kitties as well as should be used with care in tiny pet dogs.

Diphenoxylate should be prevented in pets with an overactive thyroid, kidney impairment, head injury, colic, lung condition or liver disease.

Diphenoxylate could connect with other drugs. Talk to your vet to identify if other medicines your family pet is getting can engage with diphenoxylate. Such drugs include particular antihistamines, tranquilizers, barbiturates and monoamine oxidase inhibitors.
The most usual unfavorable effects are irregularity and sedation.

Diphenoxylate’s use in felines is debatable and need to be stayed clear of.

How Lomotil (Diphenoxylate) Is Supplied

Diphenoxylate is available in 2.5 mg tablets or liquid (integrated with atropine).

Dosing Information of Lomotil (Diphenoxylate) for Dogs and Cats

Drug ought to never be carried out without first consulting your vet.
Fluid diphenoxylate is dosed at 2 to 15 ml four times daily for diarrhea.

In pet dogs, diphenoxylate is dosed at 0.05 to 0.1 mg per extra pound (0.1 to 0.2 mg/kg) 2 to 3 times daily. For coughing, diphenoxylate is dosed at 0.1 mg to 0.2 mg each extra pound (0.2 to 0.4 mg/kg) every 8 to 12 hours.

In pet cats, diphenoxylate is dosed at 0.025 to 0.05 mg each pound (0.05 to 0.1 mg/kg) twice daily. This is questionable and many veterinarians avoid using diphenoxylate in felines, particularly young kittycats.

The duration of management depends on the condition being treated, action to the drug and the growth of any type of unfavorable results. Be specific to complete the prescription unless especially directed by your vet. Even if your pet really feels far better, the entire treatment plan ought to be finished to stop relapse or stop the growth of resistance.


What is the function of lomotil?

Lomotil is a mix of two medicines, diphenoxylate and also atropine. It is utilized to deal with intense looseness of the bowels (diarrhea of restricted duration). Diphenoxylate is a man-made numbing chemically related to meperidine (Demerol).

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